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Product/Service >> Herb Powder 100g >> Kariyat Powder - 100g

Kariyat Powder - 100g - คลิกที่นี่เพื่อดูรูปภาพใหญ่
Kariyat Powder - 100g






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Kariyat Powder - 100g

Code: 000290
Regular Price: 60.00 THB (Ref. 2.14 USD) 
Special Price: 50.00 THB (Ref. 1.79 USD)
You Save: 10.00 THB (Ref. 0.36 USD)
Description:

 

Andrographis paniculata is a herbaceous plant in the family Acanthaceae, native to India and Sri Lanka.

It is widely cultivated in southern Asia, where it is used to treat infections and some diseases, often being used before antibiotics were created. Mostly the leaves and roots were used for medicinal purposes.

Pharmacology
Andrographis paniculata plant extract is known to possess a variety of pharmacological activities. Andrographolide, the major constituent of the extract is implicated towards its pharmacological activity. A study has been conducted on the cellular processes and targets modulated by andrographolide treatment in human cancer and immune cells. Andrographolide treatment inhibited the in vitro proliferation of different tumor cell lines, representing various types of cancers. The compound exerts direct anticancer activity on cancer cells by cell cycle arrest at G0/G1 phase through induction of cell cycle inhibitory protein p27 and decreased expression of cyclin dependent kinase 4 (CDK4). Immunostimulatory activity of andrographolide is evidenced by increased proliferation of lymphocytes and production of interleukin 2. Andrographolide also enhanced the tumor necrosis factor α production and CD marker expression, resulting in increased cytotoxic activity of lymphocytes against cancer cells, which may contribute for its indirect anticancer activity. The in vivo anticancer activity of the compound is further substantiated against B16F0 melanoma syngenic and HT 29 xenograft models. These results suggest that andrographolide is an interesting pharmacophore with anticancer and immunomodulatory activities and hence has the potential for being developed as a cancer therapeutic agent.

The herb is the well-known drug Kalmegh 'green chiretta', and forms the principal ingredient of a reputed household medicine ('alui'), used as a bitter tonic and febrifuge.


[edit] Phytochemistry
Andrographolide is the major constituent extracted from the leaves of the plant which is a bicyclic diterpenoid lactone. This bitter principle was isolated in pure form by Gorter (1911). Andrographolide is also attributed with such other activities like liver protection under various experimental conditions of treatment with galactosamine (Saraswat et al, 1995), paracetamol (Visen et al, 1993) etc. The hepatoprotective action of andrographolide is related to activity of certain metabolic enzymes (Choudhury and Poddar, 1984, 1985; Choudhury et al, 1987). Systematic studies on chemistry of A. paniculata had been carried out by various researches during various times.

Source: http://en.wikipedia.org/wiki/Andrographis_paniculata

Weight : 100 g.

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